diff --git a/plugins/inputs/cloudwatch/cloudwatch.go b/plugins/inputs/cloudwatch/cloudwatch.go
index 043bab390..dc2ae90fa 100644
--- a/plugins/inputs/cloudwatch/cloudwatch.go
+++ b/plugins/inputs/cloudwatch/cloudwatch.go
@@ -182,14 +182,19 @@ func (c *CloudWatch) initializeCloudWatch() error {
 		return err
 	}
 
-	cfg, err := c.CredentialConfig.Credentials()
+	awsCreds, err := c.CredentialConfig.Credentials()
 	if err != nil {
 		return err
 	}
-	c.client = cwClient.NewFromConfig(cfg, func(options *cwClient.Options) {
-		// Disable logging
-		options.ClientLogMode = 0
 
+	var customResolver cwClient.EndpointResolver
+	if c.CredentialConfig.EndpointURL != "" && c.CredentialConfig.Region != "" {
+		customResolver = cwClient.EndpointResolverFromURL(c.CredentialConfig.EndpointURL)
+	}
+
+	c.client = cwClient.NewFromConfig(awsCreds, func(options *cwClient.Options) {
+		options.EndpointResolver = customResolver
+		options.ClientLogMode = 0
 		options.HTTPClient = &http.Client{
 			// use values from DefaultTransport
 			Transport: &http.Transport{